Cyprus Turkish Journal of Psychiatry & Psychology Vol.4 Issue.3
Doi:10.35365/ctjpp.22.3.08
REVIEW ARTICLE / DERLEME YAZISI
The Role of MicroRNAs in Diagnosis and Treatment of Schizophrenia
Şizofreni Tanı ve Tedavisinde MikroRNA’ların Rolü
Elif Betül Kagızman1, Orcun Avsar2
Abstract:
Schizophrenia is a clinical disease that usually progresses with hallucinations or delusions, varies to other functional impairments, and progresses with chronic and frequent relapses. MicroRNAs (miRNAs) that are post-transcriptional regulators of gene expression are small, endogenous, non-coding, highly conserved single-stranded RNA molecules with a length of 22-25 nucleotides. Studies conducted in recent years have demonstrated that miRNAs are implicated in the pathogenesis of schizophrenia, and might be used as potential biomarkers and are significant for the treatment of these kind of disorders. In the present study, the relationship between schizophrenia and microRNAs and its significance in terms of diagnosis and treatment will be clarified, in the research, “document scanning-literature scanning” method was used as a way of data collection.
Keywords: Schizophrenia, miRNA, Biomarker
1BSc, Department of Molecular Biology and Genetics, Hitit University, Corum, Turkey, Orcid ID: 0000-0002-0328-8623
2Assist. Prof., Department of Molecular Biology and Genetics, Hitit University, Corum, Turkey, Orcid ID: 0000-0003-3556-6218
Address of Correspondence/Yazışma Adresi: Hitit University, Faculty of Arts and Sciences, Department of Molecular Biology and Genetics, Corum, Turkey, Email: [email protected]
Date of Received/Geliş Tarihi: 04.08.2020, Date of Revision/Düzeltme Tarihi: 12.05.2022, Date of Acceptance/Kabul Tarihi: 02.06.2022, Date of Online Publication/Çevirimiçi Yayın Tarihi: 13.09.2022
Citing/Referans Gösterimi: Kagızman, E, B. & Avsar, O. (2022). The Role of MicroRNAs in Diagnosis and Treatment of Schizophrenia, Cyprus Turkish Journal of Psychiatry & Psychology, 4(3): 278-287
© 2022 The Author(s). Published by Cyprus Mental Health Institute / Cyprus Turkish Journal of Psychiatry and Psychology (www.ktppdergisi.com). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 license which permits use, sharing, adaptation, distribution and reproduction in any medium or format, provided the original work is properly cited and is not used for commercial purposes. https://creativecommons.org/licenses/by-nc-sa/4.0/